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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '809eb20dcf213a17cb207bdbf2a84b694ff9c8bcd79055a548898526d0d1a47e' 
  AND token = 'U8dKFmUxBtSroVvEneihgnVjE2DMUS2Lsj06MQN4bXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}