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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '138260b6e237ba32ad736d7a4f50453dbd27f38de631cac25c06fdd91eb4859a' 
  AND token = 'wDsWK1lcujZZPTetYNFgOMvQu9rZO1tJWob46Y4/7y4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}