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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b320fdec0c0198a97e6712d433e50bf375218669470fe022d2f25795e87cb43c' 
  AND token = 'dC5WMD8s2rrXkkI8QFAAXrl5XQedJu4dz+DB1uPj7Xo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}