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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bb3307f40a45de643d1f88906a60d2b78ca52d4ad830ccd1066fedb0e428b09' 
  AND token = '+lVHC4uiQrvz2h057Xs8VmyKbDvSoj+vfCGzuR1Oa40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}