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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a3511d78e10b6de46ef98fc57531b79ce1a483a728598e4101cab9cd0c78fc0' 
  AND token = 'VzkgDtvs11Ox3ss9wOgTn9jpPcR5/ravTK4ENJ0Q/Uc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}