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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d5d6de1702414713fbef1b4e23933e71d5e8247b95ff5ac50a3561a1bc5b0f5' 
  AND token = '3Dxu9Y4Q6Uyi1puDzfGPN6GnRfPvN67KSrLF+THkLXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}