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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a135d4ddc3676205652f6b39471565bf7815e025fcf3da84ebc4d4ac78e54174' 
  AND token = 'GpTp2F/vnDWlc/E88iOj0B/k5aLzYtFpOuJN524sZBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}