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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c2401fc4cc545a8f3b5f334c5a6e496174d1060580c0d2cd9ff73c04af6bf43' 
  AND token = 'ZuvlUrPd9X2xksdC9aYlt/O9CnBWTSOPQWWVya87DaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}