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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b73fc15ae29daf1407320accc42e288ca295e4fc49f61e2ea37f6447d9edc2a' 
  AND token = 'fZ1sbydrH3O+JAjSSXqIsyeWQso0110QrRSLaVz1DbI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}