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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b91feaa414979f70dd26631293384c59e96665461218005f56d11d722955a48' 
  AND token = '/uhUdGK4GmWHYPXbJHU8J28oI6yJxs2tmCp2bcf9s70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}