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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6787b3261db20c0f7c23b600cafed9f7dbed1030208d78cea1d7e170ca53f3dc' 
  AND token = 'jE4IRokfS7cAbY6RVkR9sXBrmn2zAJvC9hXBXhwQ1Lo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}