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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f021e060c16b68fee4764be52463f31090a35d1586a0015c1969d7cc9e01fadd' 
  AND token = 'X2z8DrKzYen3CxMAAMM2PdnyNssjOJeNQfaGmKbbi4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}