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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '195add6d3f015c93127fc653cd007aa2b3f94093e85890928d3b9b5dc907d57a' 
  AND token = 'jtsgjd89cyvAalD3mAp9UBFhxMUxZRJFh4A1oUqi0Ds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}