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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7659ed2be11e505366e5144f101917a0172bb0dc4d958dc1db6dd72cccd9ccd8' 
  AND token = 'AwWgQxFvme1vK4mt9zTOd4qCD7R+LtpP5Cgvn1HLn5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}