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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '395916352dc17017837a0fb2dd0333029e4b5c1fbc65dfebe234339a87e57783' 
  AND token = 'KN3Q57lKv6nb63snP03NVxUEYPGFIqBSdv/LvJmwQsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}