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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee7de0752dc6e022ee61c1867f1874d8f8fe8c03f0ec24a1fa9213697c1b2667' 
  AND token = '+kJTS+jBwMjSrqS/fBTrlSQZHRKSwEc/HN7mBzOHT1M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}