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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b95b1a7225fae7215e2a13f2f33e27ba3989c2d31126b0c73421633a75d0744d' 
  AND token = 'Yyb/BftSceRsIhwkQSOGMZ9WILWbvE2UHbel05YinGg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}