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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f574775065e36e53bdb2dee7060eb5ff3e4a1059a77beb679f21e8603a1ee612' 
  AND token = '+izZGEuZVb2Tq1aYXjfuxoa3ReYryCkO5BUVeswP3/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}