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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ca1104bf927842294c03ee02804746e01b9098528429c9d9378ef3dbdf23958' 
  AND token = 'p8KrV3pLKOdF8ZNdltLaxJVtA/APAlNOfa1MlsW3fdU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}