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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac25e32c5cbeaff6b22f61b495bd232f32412ff368bf5bdbac1e7646ee42b2cc' 
  AND token = 'm++We3gRoVJFH6Wp5sTKP5C/eFNgoWmn8aZfaz0JAc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}