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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12c76d894530481973686ad2c63b45984e069d1a86532c6ecae6648c1b10c321' 
  AND token = 'seJdhubCg/x7r3hjxAgZF+29+Y57mJlxpJQBfFg16SY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}