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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59cc1e696317d87761363a05177843dcab20a271f30a106dfa1e4adf71a5a85e' 
  AND token = 'ghf+53VBRUFvvRGAkuB9/F2h3YHsDFDQuIk8Yt9sLlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}