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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9aaec5fa63c4ef9187660fa07c0621c2698e9f42150c47d3b610e02a38a1221' 
  AND token = 'JLTOnZ2opPocyV2uKFr4MLKIt5eaqqm+2bC5j2m1m1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}