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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82f1aaad95b6f2a37ae303b24aa084652821f29a1cb8af4a97526ee2964a1ad8' 
  AND token = '4bAZ+M0+7f/t/XdmD+bhXLLDXg6raW0RDl5+CxEk1Xk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}