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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1597103f4f02ab78e633a253e107f0556957510b0e4a81082941b8450eaa400' 
  AND token = 'kX3rn66aeIn34QFyLpfJvrty+D21K0fugWtqdUMMOAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}