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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae5b64bef186f757fe3d8d063f09095d52005b7bc7d555c3f836af35029c992d' 
  AND token = 'JEvG+6LRDaLsUHVCkOZuQ1MIm8R7rERWL8r2/7lEyEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}