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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48dcaea2dc6a6af398248bdd921ad4c9fa41aaf8526098b12781db7297e2b5ed' 
  AND token = 'cL9dlQreVeNBmMN57ZyGIZyoZ0BDfSgP1am5m5hb3ac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}