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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd707d6507f532df0630489903b68a42695ac1cca8249e9339703b5f2768cd4cc' 
  AND token = 'zIiAUWQaioaidibPROF5ADRAp9DFejEx1Geh0IzeX98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}