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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6185febd3b21102583093f5a05db029b1ee133e128e3d34885393bd804d0ee38' 
  AND token = 'V/ugBLMpEqIL4FDuuU+IcgzNVCYRt9FX29VGDs3WeuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}