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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9f1d8b63e877bf12e15585083931ce5ce302b7bcb3d2039e5658494c22d1190' 
  AND token = 'sEvbzIYax0XcxTqIRoBDEVC9PMo9/kNTqHHOYJ2KfWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}