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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '462d42979cebd64fa702c3a0503f3321ad21aaa6d42240bd445152421cbc28da' 
  AND token = 'Kw2xTxe05r0LkBdpqTrTBRKuihLIwHbz4OA5R2ZhUXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}