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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73df156cd875e71544adb5d0f55fe1369f15b9458e46154d6f48bec528d74c09' 
  AND token = 'X3FJaQsS2cMgNBPMkUacEaWi4C+WHFX2ixAq49IM7Ik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}