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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '388aa6a1f207c72991adc700b431f8920dfe5f3f0c3c51e8a769a568edc67d44' 
  AND token = 'Afs5XYkSrUw5yrWUX3kkAADYTWrIPQu58BFfKJOqSEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}