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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec4f3d79a3e1094bbd9a5fb40003b7f1add26b6749e0d96b3f718019c6464046' 
  AND token = 'amP/NjRjT7nhUQ/2q1aghlMXjX4EuYhoNAcDGDvGWt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}