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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2deddb7f2b03c04c488354e38cb838ad9f15e2fc7b9020d5ea0ad3894766fe8' 
  AND token = 'guZk3xONYr9CcuWrh+RPsezwvsbg+1rJgo/KIIrnRac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}