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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f7cd0c159a1c17c23f08e2236f97ab778ff99733b6f7bd9d2101543a000e2dd' 
  AND token = 'PWT+el/yI/Gf/HqN7YIO1zsKfvkzkW0V3tpmSkI9HCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}