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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b163016bdb783bf222e15026e852e97b213f90944c132e58e3ecb4602d251b6c' 
  AND token = 'Z6dW1iLpMmb1lMbPlf8q2b8atl2XjdbxR4t6+aJ766w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}