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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65c277ee68604135dedd6a882d2fa0321af3a3d7f228f8fe0b06141177236b02' 
  AND token = 'YhgC9SmBTYes8K9cP9aZE3fQ3st0xOiQHSXc8rfM6Ro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}