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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c166fb719162eab8a8679dbac3c68d0fd21b4ab5d5a8f571f903dd48ef3ed2a' 
  AND token = 'Du8L47iMOLivgRuTWy9QclXMfG10oxGh5K+7+NB2Uas=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}