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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1982242691349d3c0c179360e30b8e65d40cc28f55d4ce7eefcd13744a898dc5' 
  AND token = 'NtMTdPSGCYUW7pxIrXpImS1a6Uf3eAkIrYn2KOmMJnM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}