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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e003cad1912d412c08f5366f07a5e0fb63017135a9db68333727c37b60f2104' 
  AND token = 'fm8G7ojkx+Gn9B9PCrfefCHwMy9Db3fnThLspGIvU+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}