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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff9caf8cb13f45e79070574463fa81f2f672c5e8479f4b9a9399fc840621e678' 
  AND token = 'zlB1dYOqE8PGItRMPv3vdZ90qa9vHqb0bfBJ5cWt8jg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}