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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fab3a3198aa23bfd679f32e3644612e6f36d67715f1368255e9347e5ac0e16e2' 
  AND token = 'qMu0eKBfu0ZneCqppDo9bJUPA3cQ7dyJ8xPFn9rpANk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}