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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e2f6f15450599b834e6aaf3b3ed5641a45f76904498c47c4f815ee2c390ecad' 
  AND token = 'oU2Hra57vVrnQhY21tgX3/OxNAUAj5s4yLWwRkDPoBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}