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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f227244414556dfcf1fe5883ffea381f9e1293f7bca6d43ce08ea8802570b54c' 
  AND token = 'wH+jwbjJxeNnpz46z/5rmg9CRoxTaw9BM35kPXAhM44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}