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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e752ba80e1709244891b3c25e475e653682fb450b150f7359a5483d3c5c0345' 
  AND token = 'XWsyWPIF2We+SNaY8UocfeMS/t+843qDWYsNKPoffZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}