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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd738490e06bb08dd792bf87b8b018d92ab59ccb5b184b3e208fce37fc60ed0f3' 
  AND token = 'vS+1y6W9X2WS/C4fF6faDKy0JxZGvC+1i+VsiPX6Zdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}