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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65e7290419d4acbfd6b51b4fde93c83eae16d370ee086f4c5e8735210a9f894e' 
  AND token = '4b9kdPDCcwaitAnMx3gPh//NPCqtrLq2IgamWUFAWoc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}