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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7344cd68c039501b75edbb6d3f98c21a06ea878b95a1e4a6af72ad4d008e2e0' 
  AND token = 'OqWCakUB622zIxtRY6Llq+ttbQdTT6xG/RMdqQe1PiU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}