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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d4b3bf1c2639d3106dd3e367e994f5e2bcca5c6cc2380d7cd0c306289e66287' 
  AND token = 'oRYcjOw4l8/sXZhF+XCVG34QhNd/SqrAMWjE/eiLU44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}